Archiv der Pharmazie p. 709 - 713 (1984)
Update date:2022-08-04
Topics:
Troschutz
2,4,6-Triaminopyrimidine is reacted with 3,4,5-trimethoxybenzylidene-1,3-dicarbonyl compounds to yield Michael adducts which are cyclised in acidic medium to the 5,8-dihydropyrido[2,3-d]diamines. The title compounds posses a rigid trimethoprim structure and are of interest as potential inhibitors of dihydrofolate reductase (DHFR).
View MoreFOSHAN NANHAI ZHONGNAN PHARMACEUTICAL FACTORY
Contact:0086-0757-85609331
Address:XIAHENGTIAN INDUSTRIAL ZONE,SHAYONG VILLAGE,LISHUI TOWN
Anqing World Chemical Co., Ltd.
Contact:+86-556-5800026
Address:Daguan Economic Development Zone of circular economy industrial park Anqing City Anhui province
Shao Xing Empire Import&Export CO.,ltd
Contact:86-575-82127757
Address:11#, Weiwu Road, Shangyu Industrial Park, Hangzhou Bay, Hangzhou, Zhejiang Province, China
Shanghai Yuking Water Soluble Material Tech Co., Ltd
Contact:86-21-68286299
Address:4F, 13B, No. 600, South Xinyuan Road 201306, Shanghai, China
Huangshi Meifeng Chemical Co.,ltd.
Contact:+86-714-6516706
Address:1941-4-3#,Hubin Avenue,Huangshi,Hubei,China
Doi:10.1016/j.tet.2006.11.062
(2007)Doi:10.1080/00397910600945894
(2006)Doi:10.1021/jm060878m
(2007)Doi:10.1021/ja067975p
(2007)Doi:10.1021/ja00026a028
(1991)Doi:10.1021/jm3012992
(2012)
