Journal of Pharmaceutical Sciences p. 1168 - 1170 (1984)
Update date:2022-08-05
Topics:
Foye
An
Maher
A simple method for obtaining the title compounds was found in the alkaline rearrangement of S-2-aminoethylisothirouronium salts, which were obtained from the condensation of thiourea or substituted thioureas with 2-bromoethylamine hydrobromide. No activity was found for the substituted guanidines against P388 lymphocytic leukemia in mice, or as H2-receptor antagonists.
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