A useful α, α' - Annulation reaction of enamines

DOI: 10.1016/S0040-4020(98)00788-1

Source and publish data:

Tetrahedron p. 12721 - 12736 (1998)

Update date:2022-08-02

Topics:

Authors:

Frontier, Alison J.

Danishefsky, Samuel J.

Koppel, Gary A.

Meng, Dongfang

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Article abstract of DOI:10.1016/S0040-4020(98)00788-1

The reactions of a series of enamines generated from a range of cyclic ketones with chloromethyl and iodomethyl vinyl ketone have been studied. The principal products are bridged ring diketones. The four carbon bridge, bearing a 2-oxobutyl function, spans

Full text of DOI:10.1016/S0040-4020(98)00788-1

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