A useful α, α' - Annulation reaction of enamines

Article abstract of DOI:10.1016/S0040-4020(98)00788-1

The reactions of a series of enamines generated from a range of cyclic ketones with chloromethyl and iodomethyl vinyl ketone have been studied. The principal products are bridged ring diketones. The four carbon bridge, bearing a 2-oxobutyl function, spans