Synthesis of Ethyl (2RS,3SR)-1-Tosyl-3-vinylazetidine-2-carboxylate and Ethyl (2RS,E)-3-Ethylidene-1-tosylazetidine-2-carboxylate (=rac-Ethyl N-Tosylpolyoximate)

DOI: 10.1002/hlca.19880710513

Source and publish data:

Helvetica Chimica Acta p. 1025 - 1034 (1988)

Update date:2022-08-04

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Authors:

Baumann, Hans

Duthaler, Rudolf O.

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Article abstract of DOI:10.1002/hlca.19880710513

The synthesis of 3-ethylideneazetidine-2-carboxylic acid (=polyoximic acid; 3) is approached in two different ways leading to potential precursors of 3.The first way involved a ring closure to a vinyl-substituted azetidine.Thus, Ireland-Claiser rearrangem

Full text of DOI:10.1002/hlca.19880710513

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