Use of methylene chloride as a C1 unit in N,N-dialkylaminomethylation reaction

Article abstract of DOI:10.1080/00397919308009843

Mannich products have been isolated in good yields with methylene chloride as a C1 unit, instead of formaldehyde. It is evidenced that, contrary to previous understanding, a high pressure procedure is not necessary required and that the methylene bisamines function as intermediates.

Full text of DOI:10.1080/00397919308009843

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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Use of Methylene Chloride
as a C1 Unit in N,N-
Dialkylaminomethylation
Reaction
Florence Souquet a , Thierry Martens a & Maurice-
Bernard Fleury a
a Laboratoire de Chimie Analytique et
Electrochimie, URA CNRS 1310, Faculté de
Pharmacie , 4, Avenue de l'Observatoire, 75270,
Paris Cedex, 06
Published online: 23 Sep 2006.
To cite this article: Florence Souquet , Thierry Martens & Maurice-Bernard Fleury
(1993) Use of Methylene Chloride as a C1 Unit in N,N-Dialkylaminomethylation
Reaction, Synthetic Communications: An International Journal for Rapid
Communication of Synthetic Organic Chemistry, 23:6, 817-828
To link to this article: http://dx.doi.org/10.1080/00397919308009843
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