Direct functionalization of 4,5-dichloropyridazin-6-one

DOI: 10.1002/jhet.5570360413

Source and publish data:

Journal of Heterocyclic Chemistry p. 905 - 910 (1999)

Update date:2022-08-05

Topics:

Authors:

Chung, Hyun-A

Kweon, Deok-Heon

Kang, Young-Jin

Park, Jung-won

Yoon, Yong-Jin

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Article abstract of DOI:10.1002/jhet.5570360413

Direct functionalization of 4,5-dichloropyridazin-6-one with some nucleophiles in seven solvents gave regioselectively 5-halo- 4-substituted-pyridazin-6-ones as main product. Reaction of 4,5- dichloropyridazin-6-one with 2-mercaptopyrimidine (2 equivalents) also afforded 4,5-di(pyrimidin-2-ylsulfanyl)pyridazin-6-one as the main product.

Full text of DOI:10.1002/jhet.5570360413

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Product name:4-ethylamino-5-chloropyridazin-6-one

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