Journal of the American Chemical Society p. 3830 - 3831 (2007)
Update date:2022-08-04
Topics:
Biddle, Margaret M.
Lin, Michael
Scheidt, Karl A.
The enantioselective synthesis of flavanones and chromanones is described. Bifunctional thiourea catalysts promote an asymmetric oxo-conjugate addition to a β-ketoester alkylidene in high yields with excellent enantioselectivity (80-94% ee) for aryl and alkyl substrates. Decarboxylation of the β-ketoester proceeds smoothly in a one-pot procedure to afford the enantioenriched flavanones and chromanones. Copyright
View MoreXinchang Jiu Xin Pharmaceutical Co., Ltd
website:http://www.jiuxinpharm.com
Contact:86 137 5756 8585
Address:Poyang industry Park
Contact:+86-512-56795332
Address:No227 Shuanglong Rd, Fenghuang, Zhangjiagang
Synchem Pharma Co.,Ltd(expird)
Contact:+0086-21-61984905-1
Address:Building 60,Zimian Park, LongYang industrial Area, 1515Nong，Yuandong Road Fengxian District, Shanghai ,China
Changsha Goomoo Chemical Technology Co.Ltd
Contact:+86-731-82197655
Address:No.649,Chezhan Rd.(N),Changsha,Hunan,China
Contact:86-25-58619180
Address:Nanjing High-Tech Zone 10 Xinghuo Road Pukou District Nanjing, Jiangsu 210061 The People's Republic of China
Doi:10.1002/ejoc.200600868
(2007)Doi:10.1055/s-0036-1588422
(2017)Doi:10.1021/jo01050a549
(1962)Doi:10.1002/chem.200903158
(2010)Doi:10.1016/j.tet.2008.11.103
(2009)Doi:10.1021/acs.orglett.0c04114
(2021)
