Journal of Medicinal Chemistry p. 248 - 252 (1985)
Update date:2022-08-04
Topics:
Colbry, Norman L.
Elslager, Edward F.
Werbel, Leslie M.
The synthesis and antimalarial activity of a series of 2,4,6-triaminopyrido<3,2-d>pyrimidines (4) is described.Several 6-substituted benzylmethylamino analogues were more active against trophozoite induced Plasmodium berghei in mice than the corresponding quinazoline analogues.These agents, however, are cross-resistant to other antifolate compounds and are thus of limited potential as human agents.
View MoreTaizhou Sunny Chemical Co.,Ltd
Contact:+86-523-86920899 +86-13951172783
Address:No.11 Xingyuang road, Gaoyong Chemical Industry Park, Gaogang Jiangsu China
Shanghai Send Pharmaceutical Technology Co., Ltd.
website:http://www.shsendpharma.com
Contact:021-58088081, +8613585868794
Address::Room A601, Building 1,NO. 800 Qingdai Road Pudong District Shanghai,China
Binzhou Holly Pharmaceutical Co.,Ltd.
Contact:74517
Address:No.15 Dapu Road,Huangpu District Shanghai,P.R.China
Anhui Jiatiansen Agrochemical Co.,Ltd
Contact:15366811918
Address:chemical industrial park,xiangyu town,dongzhi county,anhui,china
QINGDAO NEW FLOURISH INTERNATIOANAL TRADE CO., LTD.
Contact:+86 532 80861829
Address:No. 1, Yinchuan East Road, 266061, Qingdao, China
Doi:10.1016/j.bmcl.2007.01.083
(2007)Doi:10.1016/j.ica.2006.10.043
(2007)Doi:10.1021/jo01018a026
(1965)Doi:10.1021/ja01258a053
(1942)Doi:10.1021/jo030378q
(2004)Doi:10.1016/j.bmc.2007.02.049
(2007)
