Chemical and Pharmaceutical Bulletin p. 2219 - 2224 (1994)
Update date:2022-08-02
Topics:
Oishi
Iwamoto
Okada
Suzuki
Tanji
Miyashita
Higashino
1-Chlorophthalazine (1) reacts with a 2-fold molar excess of ynamines 2a, b to give penta-substituted pyridine derivatives 3a,b by nitrogen-nitrogen bond cleavage of the pyridazine ring with release of hydrogen chloride. Similarly, other fused pyridazines having a chloro substituent α to nitrogen in the pyridazine ring, i.e., pyrido[3,4-d]- (10a), pyrido[2,3-d]- (10b), thiazolo[4,5-d]- (10c, d), furo[2,3-d]- (10e) and pyrrolo[2,3-d]- (10f, g) pyrfdazine derivatives, gave the corresponding penta-suhstituted pyridines 11a-11k.
View MoreContact:+86-579-85206992
Address:No 451 chouzhou north road ,room 1106 int'l business center , yiwu ,china
website:http://www.tcfinechem.com/
Contact:18681346930
Address:baifu town,whou district
Zhejiang Kaili Industrial Co., Ltd
Contact:+86-571-85241926
Address:lantian business center,No.18 Moganshan Road
Wuxi Highness Chemical Co.,Ltd
website:https://www.phtpharmatech.com/
Contact:86-510-81771080
Address:No58 East Xinguan Rd, Guanlin Town, Yixing City, Jiangsu China
Zhejiang Rongkai Chemical Technology Co.,Ltd.
Contact:+86-578-8185786
Address:Shangjiang Industrial Zone,Suichang
Doi:10.1016/S0040-4039(00)02243-7
(2001)Doi:10.1021/ma60043a015
(1975)Doi:10.1002/jhet.5570370608
(2000)Doi:10.1016/S0022-328X(00)00624-0
(2001)Doi:10.3390/molecules18066883
(2013)Doi:10.1016/S0022-328X(01)00957-3
(2001)
