Chemical and Pharmaceutical Bulletin p. 2219 - 2224 (1994)
Update date:2022-08-02
Topics:
Oishi
Iwamoto
Okada
Suzuki
Tanji
Miyashita
Higashino
1-Chlorophthalazine (1) reacts with a 2-fold molar excess of ynamines 2a, b to give penta-substituted pyridine derivatives 3a,b by nitrogen-nitrogen bond cleavage of the pyridazine ring with release of hydrogen chloride. Similarly, other fused pyridazines having a chloro substituent α to nitrogen in the pyridazine ring, i.e., pyrido[3,4-d]- (10a), pyrido[2,3-d]- (10b), thiazolo[4,5-d]- (10c, d), furo[2,3-d]- (10e) and pyrrolo[2,3-d]- (10f, g) pyrfdazine derivatives, gave the corresponding penta-suhstituted pyridines 11a-11k.
View MoreContact:732.938.2777
Address:5012 Industrial Road Farmingdale, NJ 07727
ChangZhou XiaQing Chemical Co., Ltd.
Contact:+86-519-88721665
Address:3# Hengluo Road, Henglin Town, Changzhou City, Jiangsu Province，China
Contact:13120882795；+86-21-34621078;+86-021-31122318
Address:Suite 2,No.2715 Longwu Road
Jining tiansheng chemical co.,ltd.
Contact:+86-537-5158722
Address:ROOM 1011, BLOCK B, CUIDU INTERNATIOAL BUSINESS CENTER, JINING CITY, CHINA
Kaymossy BioChem Tech Co., Ltd
website:http://www.kaimosi.com
Contact:0571-87191913/0571-87199097
Address:Room 215, Building 3rd, No.288 Ningxia Road, Qingdao city, China
Doi:10.1016/S0040-4039(00)02243-7
(2001)Doi:10.1021/ma60043a015
(1975)Doi:10.1002/jhet.5570370608
(2000)Doi:10.1016/S0022-328X(00)00624-0
(2001)Doi:10.3390/molecules18066883
(2013)Doi:10.1016/S0022-328X(01)00957-3
(2001)
