Organic Letters p. 2043 - 2046 (2007)
Update date:2022-09-26
Topics: Antagonist Isolation Total synthesis Biological Assays Reaction Conditions Spectroscopic Analysis Natural product Anibamine
Li, Guo
Watson, Karen
Buckheit, Robert W.
Zhang, Yan
The total synthesis of anibamine, the first and only natural product known as a chemokine receptor OCR5 antagonist, is reported herein. Anibamine was synthesized from acetylacetone and cyanoacetamide in 10 steps.
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Doi:10.1016/j.tet.2007.03.132
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