Organic Process Research and Development p. 290 - 295 (2015)
Update date:2022-08-05
Prashad, Mahavir
Liu, Yugang
Shieh, Wen-Chung
Schaefer, Frank
Hu, Bin
Girgis, Michael
An efficient process was developed for the manufacture of MSA100, a serotonin receptor antagonist, via a five-step synthetic route furnishing a high quality of active pharmaceutical ingredient. Highlights of this synthesis include: (1) replacing carcinoge
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