A NEW BASE-CATALYZED CLEAVAGE REACTION FOR THE PREPARATION OF PROTECTED PEPTIDES

DOI: 10.1016/S0040-4020(01)98798-8

Source and publish data:

Tetrahedron p. 4237 - 4244 (1984)

Update date:2022-07-29

Topics: Preparation Experimental conditions

Authors:

Whitney, Donald B.

Tam, James P.

Merrifield, R. B.

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Article abstract of DOI:10.1016/S0040-4020(01)98798-8

A new base-catalyzed elimination reaction employing the hindered, non-nucleophilic bases tetramethylguanidine or 1,8-diazabicyclo-<5.4.0.>-undec-7-ene has been developed for the removal of protected peptides from a 2-<4-(hydroxymethyl)phenyl-acetoxy>propi

Full text of DOI:10.1016/S0040-4020(01)98798-8

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