Journal of Heterocyclic Chemistry p. 1191 - 1194 (2007)
Update date:2022-07-29
Topics:
Goswami, Shyamaprosad
Jana, Subrata
Hazra, Anita
Adak, Avijit Kumar
(Chemical Equation Presented) A series of functionalized, aryl substituted naphthyridines and quinolines has been synthesized by microwave-assisted one-pot two-component synthesis under solvent-free conditions in good yields by the reaction of a variety of aryl or heteroaryl amines and aryl vinyl ketones. A combinatorial type approach for a one-step microwave reaction has been developed where a ring-closing condensation is followed by a spontaneous aromatization to afford the functionalized aryl substituted 1,8-naphthyridines and quinolines.
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