Ellipticine Derivatives with an Affinity to the Estrogen Receptor, an Approach to Develop Intercalating Drugs with a Specific Effect on the Hormone-Dependent Breast Cancer

DOI: 10.1021/jm00383a010

Source and publish data:

Journal of Medicinal Chemistry p. 752 - 761 (1985)

Update date:2022-09-26

Topics:

Authors:

Delbarre, Alain

Oberlin, Robert

Roques, Bernard P.

Borgna, Jean-Louis

Rochefort, Henri

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00383a010

In order to obtain breast tumor directed agents, we have prepared mixed compounds using estradiol or (E)-clomiphene as specific vectors for the breast tissue and a DNA intercalator from the ellipticine series as cytotoxic agent.Among the newly synthesized

Full text of DOI:10.1021/jm00383a010

Products guided by the article

Product name:(E)-2-<3,9-diaza-11-<4-(2-chloro-1,2-diphenylethenyl)phenoxy>-2-oxoundecamethylene>-9-hydroxyellipticinium chloride hydrochloride

Cas No:95764-51-5

R&D Labs maybe for 95764-51-5

shandong lukang animal & plant drug trading co.,ltd.

Contact:15853765968

Address:floor 9, lukang ,jingying building,#173,taibai building west road,jining city,shandong,china
ENERGYCO LTD.

Contact:+86-25-83719363

Address:106-7 Chunnan Rd, Chunxi Town, Gaochun, Nanjing, China
Shanghai Pengkai Chemical Co.,Ltd

Contact:+86-21-60526671

Address:No.4226 Duzhuang Rd Minhang District Shanghai China
Haitong Chemical Industrial Co.,Ltd.

website:https://www.haitonglongwin.com/

Contact:+86-022-66221018

Address:18-701, No.99, The 4th Street, TEDA,
Wuhan Yitongtai Science and Technology Co.,Ltd.

Contact:+86-27-88933550

Address:27th Fl. Bldg. 1, Shuian International Mansion, Heping Ave, Wuhan, Hubei, China

Relevant to this article

Application of Suzuki–Miyaura and Buchwald–Hartwig Cross-coupling Reactions to the Preparation of Substituted 1,2,4-Benzotriazine 1-Oxides Related to the Antitumor Agent Tirapazamine

Doi:10.1002/jhet.2559
(2017)
New entry for synthesis of N-acylhydrazones, pyridazinones, and 1,3,4-oxadiazin-6-ones from α-amino acid esters

Doi:10.1248/cpb.55.1652
(2007)
Preparation and Conversion of Aminodiphenylcyclopropenium Salts to 1,2,3-Triazines

Doi:10.1246/bcsj.58.1073
(1985)
Electrophilic glycosidation employing 3,5-O-(di-tert-butylsilylene)-erythro-furanoid glycal leads to exclusive formation of the β-anomer: synthesis of 2′-deoxynucleosides and its 1′-branched analogues

Doi:10.1016/j.tet.2010.04.043
(2010)
INTRAMOLECULAR HYDROGEN-BONDING IN PHENYL MONO-, DI-, AND TRI-O-METHYL-β-D-GLUCOPYRANOSIDES

Doi:10.1016/0008-6215(85)85145-4
(1985)
A Transition-Metal-Free One-Pot Cascade Process for Transformation of Primary Alcohols (RCH₂OH) to Nitriles (RCN) Mediated by SO₂F₂

Doi:10.1002/ejoc.201900478
(2019)

Article Doi