Journal of Medicinal Chemistry p. 831 - 833 (1985)
Update date:2022-09-26
Topics:
Weintraub
Blohm
Laughlin
20-(Hydroxymethyl)-4-methyl-4-aza-2-oxa-5α-pregnan-3-one and the corresponding 3-thione were synthesized with use of 20-(hydroxymethyl)-4- methyl-4-aza-5α-pregnan-3-one as the starting material. The compounds were tested in vitro for inhibition of testosterone 5α-reductase and found to be weak inhibitors with K(i)'s in the 10-7 range.
View MoreContact:+86-571-86025531 / 86024803
Address:1218-24 Guangyin Mansion,42 Fengqi East Road
Zhejiang Chemline International Co., Ltd.
Contact:+86-571-88062298
Address:Hengdian Industry Area, Dongyang, Zhejiang, China
Zhejiang Sanmei Chemical Industry Co., Ltd
Contact:86-579-87633213
Address:Huchu Industrial Zone, Qingnian Rd., Wuyi County, Zhejiang Prov., China.
Jinhua City Mingzhu Pharmaceutical Co.,Ltd.
Contact:15857995878 0579-82207761
Address:No.169 Shenze Road, New Area,Jinpan Development Zone, Jinhua
Contact:86 311 85902108 / 85902109
Address:room 1001-1005 ,huanghe Road ,shijiazhuang ,China
Doi:10.1016/0008-6215(85)85145-4
(1985)Doi:10.1002/ejoc.201900478
(2019)Doi:10.1007/BF00779077
(1977)Doi:10.1021/ja01630a020
(1954)Doi:10.1021/ja00865a027
(1962)Doi:10.1021/ja01132a042
(1952)
