Journal of Medicinal Chemistry p. 831 - 833 (1985)
Update date:2022-09-26
Topics:
Weintraub
Blohm
Laughlin
20-(Hydroxymethyl)-4-methyl-4-aza-2-oxa-5α-pregnan-3-one and the corresponding 3-thione were synthesized with use of 20-(hydroxymethyl)-4- methyl-4-aza-5α-pregnan-3-one as the starting material. The compounds were tested in vitro for inhibition of testosterone 5α-reductase and found to be weak inhibitors with K(i)'s in the 10-7 range.
View MoreNanJing Rate Biochemicals CO., LTD
Contact:+86-25-84931986
Address:NO. 1 Hongjing Road,Jiangning Science Park,Nanjing,China
Jiangxi Hito Chemical Co., Ltd.
Contact:+86-792-3170318
Address:No. 6, Tianhong Ave., Xinghuo Industry Park, Yongxiu, Jiujiang, Jiangxi, China
LIANYUNGANG YC FINE CHEMICAL CO., LTD
Contact:+86-518-858 99188
Address:Shangdong Modern Bldg, South Greenpark Road, Lianyungang, Jiangsu Pro. China
Shanghai Rainbow Chemistry Co., Ltd.
Contact:+86-21-64968086-5815/5812
Address:3rd floor, Building 7, 251 Faladi Road, Zhangjiang Hi-Tech Park, Pudong District, Shanghai, P.R. China
Penglai Qianwei Chemical Co., Ltd.
Contact:86-535-3357802
Address:Shahelu (north), Penglai, Shandong, China
Doi:10.1016/0008-6215(85)85145-4
(1985)Doi:10.1002/ejoc.201900478
(2019)Doi:10.1007/BF00779077
(1977)Doi:10.1021/ja01630a020
(1954)Doi:10.1021/ja00865a027
(1962)Doi:10.1021/ja01132a042
(1952)
