AN EFFICIENT SYNTHESIS OF (S)-CHROMANMETHANOL, A VITAMIN E PRECURSOR

Article abstract of DOI:10.1246/cl.1985.561

The (S)-chromanmethanol, a key intermediate for the synthesis of optically active α-tocopherol was synthesized by a reaction sequence which utilized the asymmetric epoxidation of the (E)-allylic alcohol to the (2R,3R)-epoxyalcohol in high enantiomeric exc