Journal of Medicinal Chemistry p. 1517 - 1521 (1985)
Update date:2022-08-05
Topics:
Slade
Stanton
Ben-David
Mazzenga
The synthesis of chiral 1,5-benzothiazepines 2a-c, 14a-c, 15c, and 16a prepared from cysteine is described. In vitro inhibition of angiotensin converting enzyme (ACE) is reported for each compound. Compound 2c was the most potent in vitro having an IC
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(1980)Doi:10.1039/b504731e
(2005)Doi:10.1021/jo00215a050
(1985)
