Angiotensin converting enzyme inhibitors: 1,5-Benzothiazepine derivatives

DOI: 10.1021/jm00148a024

Source and publish data:

Journal of Medicinal Chemistry p. 1517 - 1521 (1985)

Update date:2022-08-05

Topics:

Authors:

Slade Slade

Stanton Stanton

Ben-David

Mazzenga

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00148a024

The synthesis of chiral 1,5-benzothiazepines 2a-c, 14a-c, 15c, and 16a prepared from cysteine is described. In vitro inhibition of angiotensin converting enzyme (ACE) is reported for each compound. Compound 2c was the most potent in vitro having an IC View More

Full text of DOI:10.1021/jm00148a024

Products guided by the article

Product name:3(R)-amino>-5-(carboxymethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one hydrochloride

Cas No:96289-22-4

R&D Labs maybe for 96289-22-4

Jining Shengrun Chemical Industry Co., Ltd.

Contact:+86-537-7121666 ,

Address:West Ring Road,Wenshang County Shandong Province
Changsha Nutritopper Bio Technology Co.,Ltd.

Contact:+86-731-87803543

Address:East 1st Street, Baima Road, Ningxiang County
shanghai jiuling chemical co.,ltd.

Contact:+86-21-50387295

Address:Zaozhuang Road, Pudong, Shanghai City. China
Longhui qunfeng Chemical Co., Ltd

Contact:86-731-82173407

Address:South-east Industrial Park, Longhui County, Hunan Province, China
Shanghai Longjin Metallic Material Co., Ltd.

website:http://www.shlongjin.cn/

Contact:021-56517503,56502257

Address:No.16, Lane 555, Chengyin Road, Shanghai

Relevant to this article

Doi:10.1039/jr9620004039
(1962)
Cornusiin A, a dimeric ellagitannin forming four tautomers, and accompanying new tannins in Cornus officinalis

Doi:10.1248/cpb.32.4662
(1984)
An exact coordination mode of 6-thiopurine with an organotin(IV): Preparation and crystal structure of triphenyl(6-thiopurinyl)tin(IV)

Doi:10.1016/j.ica.2004.03.002
(2004)
The Reaction of Olefins with Chloroalkoxyalkanes and Formic Acid in Ether

Doi:10.1246/bcsj.53.1376
(1980)
Stereoselective γ-lactam synthesis via palladium-catalysed intramolecular allylation

Doi:10.1039/b504731e
(2005)
Catalytic "Homo-Reformatsky" Reaction. Ambident Chemical Reactivities of the Zinc Homoenolate of Propionate

Doi:10.1021/jo00215a050
(1985)

Article Doi