Synthesis of the cyclo- Isomers of Dolastatin 3

DOI: 10.1021/jo00215a012

Source and publish data:

Journal of Organic Chemistry p. 2654 - 2659 (1985)

Update date:2022-08-04

Topics:

Authors:

Pettit, George R.

Nelson, Paul S.

Holzapfel, Cedric W.

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Article abstract of DOI:10.1021/jo00215a012

An all-L configuration reverse order of peptide bonding possibility for the cell growth inhibitory (PS system) cyclic peptide dolastatin 3 was eliminated by synthesis of thiazole amino acid containing peptide 2.By employing a series (Schema I) of mixed ca

Full text of DOI:10.1021/jo00215a012

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