Synthesis and antihypertensive activity of 1,4-dihydropyridine derivatives with a 4-(disubstituted phenyl) ring and an aminoalkyl ester group: Highly potent and long-lasting calcium antagonists

DOI: 10.1248/cpb.40.2049

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2049 - 2054 (1992)

Update date:2022-08-04

Topics:

Authors:

Kanno Kanno

Yamaguchi

Okamiya Okamiya

Sunakawa

Takeshita

Naruchi Naruchi

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Article abstract of DOI:10.1248/cpb.40.2049

New 1,4-dihydropyridine derivatives bearing a 4-(disubstituted phenyl) ring and an aminoethyl ester or an amino-2,2-dimethylpropyl ester were synthesized and their antihypertensive activities were examined in normotensive rats and spontaneously hypertensi

Full text of DOI:10.1248/cpb.40.2049

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