A new Synthetic Model for Myoglobin: "Tulip Garden" Porphyrin

Article abstract of DOI:10.1246/bcsj.58.447

A new model compound "tulip garden" porphyrin, has a long half-lifetime, thus satisfying the demand for the synthetic analogue of myoglobin.At the same time, "tulip garden" porphyrin has high O2 affinities as compared to other protected porphyrin; especially, its Co(II) complex shows almost the same affinity (P_1/2O2) as coboglobins.The difference in oxygen affinities between "tulip garden" and "picket fence-type" porphyrins can be ascribed to the bulkiness of pendant groups.The strong "side" influence of the adamantyl group can be expected to bring about a high O2 affinity.