Cyclization of Penta- and Hexapeptide Active Esters Related to Gramicidin S and Gratisin

DOI: 10.1246/bcsj.62.594

Source and publish data:

Bulletin of the Chemical Society of Japan p. 594 - 596 (1989)

Update date:2022-08-03

Topics: Cyclization Coupling reagents Peptide Synthesis Intramolecular Reactions Experimental terms Purification techniques Gramicidin S Active esters

Authors:

Tamaki, Makoto

Takimoto, Michiaki

Hayashi, Mitsuo

Muramatsu, Ichiro

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Article abstract of DOI:10.1246/bcsj.62.594

Four pentapeptide N-hydroxysuccinimide esters related to gramicidin S were allowed to cyclize in pyridine.The peptides with a L-Phe residue preceding Pro tend to form various cyclic polimers,

Full text of DOI:10.1246/bcsj.62.594

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