Synthetic carbapenem antibiotics II. Stereoisomers of 7-hydroxyethyl-2,2,5-trimethyl-3-oxa-1-azabicyclo[4.2.0]-octan-8-one

DOI: 10.1016/S0040-4039(00)89153-4

Source and publish data:

Tetrahedron Letters p. 583 - 586 (1985)

Update date:2022-07-29

Topics:

Authors:

Shih Shih

Fayter Fayter

Cama Cama

et al. et al.

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Article abstract of DOI:10.1016/S0040-4039(00)89153-4

The titled compounds are key synthetic intermediates in the structure-activity relationship studies of novel 1-methyl carbapenem antibiotics. Preparation and structural determination of these stereoisomers by X-ray crystallography and proton NMR spectroscopy are reported.

Full text of DOI:10.1016/S0040-4039(00)89153-4

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