Synthesis of the antileukemic agent (±)-steganone using a stereoconvergent biaryl coupling reaction

DOI: 10.1021/ja00303a027

Source and publish data:

Journal of the American Chemical Society p. 4984 - 4988 (1985)

Update date:2022-08-04

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Authors:

Magnus Magnus

Schultz Schultz

Gallagher

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Article abstract of DOI:10.1021/ja00303a027

The total synthesis of (±)-steganone (4) has been achieved in a stereoselective manner from piperonal. The cinnamate derivative 15 was oxidized by using Tl(OCOCF₃)₃ in TFA to give the biaryl 26 (81%). Reduction of 26 with LiAlH₄

Full text of DOI:10.1021/ja00303a027

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