
Journal of Medicinal Chemistry p. 911 - 918 (1987)
Update date:2022-08-02
Topics:
Dillard, Robert D.
Carr, F. Patrick
McCullough, Doris
Haisch, Klaus D.
Rinkema, Lynn E.
Fleisch, Jerome H.
A series of <<(tetrazol-5-ylaryl)oxy>methyl>acetophenones was synthesized and evaluated as antagonists of leukotriene D4 induced contractions of guinea pig ileum.Substitution at the 3-position of the acetophenone with ethyl (66), propyl (68), b
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