Leukotriene Receptor Antagonists. 2. The methyl>acetophenone Derivatives

DOI: 10.1021/jm00388a028

Source and publish data:

Journal of Medicinal Chemistry p. 911 - 918 (1987)

Update date:2022-08-02

Topics:

Authors:

Dillard, Robert D.

Carr, F. Patrick

McCullough, Doris

Haisch, Klaus D.

Rinkema, Lynn E.

Fleisch, Jerome H.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00388a028

A series of <<(tetrazol-5-ylaryl)oxy>methyl>acetophenones was synthesized and evaluated as antagonists of leukotriene D₄ induced contractions of guinea pig ileum.Substitution at the 3-position of the acetophenone with ethyl (66), propyl (68), b

Full text of DOI:10.1021/jm00388a028

Products guided by the article

Product name:4-<<<(4-acetyl-3-hydroxy-2-propylphenyl)methyl>thio>methyl>benzeneacetonitrile

Cas No:97581-62-9

R&D Labs maybe for 97581-62-9

Guangzhou Probig Fine Chemical Co., Ltd.

Contact:020-86297874

Address:No.2, 1/F, No.20, Hetai Road,Hebian Village, Baiyun District,Guangzhou,China
HANGZHOU FOREWIN PHARMA CO., LTD

Contact:+86-571-89053961

Address:hangzhou
Beijing Zhongshuo Pharmaceutical T & D Co.,Ltd

Contact:0086-10-64430626

Address:ea No 16, HEPINGLI,DONGCHENG DISTRICT,BEIJING,P.R.CHINA.
feixia327@163.com

Contact:--

Address:80G, No.1 Building, Guodu Development Mansion, No. 182 Zhaohui Road, Hangzhou City, Zhejiang Province,China.
Jiangxi Hito Chemical Co., Ltd.

Contact:+86-792-3170318

Address:No. 6, Tianhong Ave., Xinghuo Industry Park, Yongxiu, Jiujiang, Jiangxi, China

Relevant to this article

One-pot synthesis of enantiomerically pure N-protected allylic amines from N-protected α-amino esters

Doi:10.3762/bjoc.12.94
(2016)
Thioimidazoline based compounds reverse glucocorticoid resistance in human acute lymphoblastic leukemia xenografts

Doi:10.1039/c5ob00779h
(2015)
(H⁺,K⁺)-ATPase inhibiting 2-[(2-pyridylmethyl)sulfinyl]benzimidazoles. 4. A novel series of dimethoxypyridyl-substituted inhibitors with enhanced selectivity. The selection of pantoprazole as a clinical candidate

Doi:10.1021/jm00084a010
(1992)
α-Amino Acids as Chiral Educts for Asymmetric Products. The Synthesis of α'-Amino-α,β-ynones

Doi:10.1021/jo00221a004
(1985)
BOTRYODIPLODIN: A MYCOTOXIN FROM PENICILLIUM ROQUEFORTI. REACTION WITH AMINO-PYRIMIDINES, AMINO-PURINES AND 2'-DEOXYNUCLEOSIDES

Doi:10.1016/S0040-4020(01)96415-4
(1985)
Optimizing of 2,3-diarylindenes as fluorescent estrogens: Variation of the acceptor group, ortho substitution of the 2-ring, and C-1 methylation

Doi:10.1021/jm00117a014
(1988)

Article Doi