Optimizing of 2,3-diarylindenes as fluorescent estrogens: Variation of the acceptor group, ortho substitution of the 2-ring, and C-1 methylation

Article abstract of DOI:10.1021/jm00117a014

In an attempt to elucidate steric and electronic factors that affect the fluorescence and estrogen receptor binding properties of 2,3-diarylindenes, we have prepared and examined the behavior of 11 analogues bearing substituents on the 1-position or on th