Reaction of α,β-Unsaturated Ketones with Urea. Synthesis and Spectral Properties of 2(1H)-Pyrimidinone Derivatives

Article abstract of DOI:10.1021/je00042a047

1,3-Diaryl-2-propen-1-ones react with urea to give 4,6-diaryl-3,4-dihydropyrimidinones (IVa-g) that can be further oxidized to the corresponding dehydro analogues (Va-f).The latter compounds are also obtained via interaction of aroylphenylacetylenes with urea.Spectral data, supporting the suggested structures IV and V, are presented.