Studies Directed at a Synthesis of Morphine Alkaloids. Regiocontrol in Robinson-Type Annelation of 2-(Hydroxymethyl)-4-oxo-3-piperidinecarboxylic Acid γ-Lactones

DOI: 10.1021/jo00223a001

Source and publish data:

Journal of Organic Chemistry p. 4421 - 4425 (1985)

Update date:2022-08-05

Topics:

Authors:

Schultz, Arthur G.

Shannon, Paul J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00223a001

Conjugate reduction of 5a with NaBH4 in THF-pyridine, followed by sequential addition of excess benzaldehyde and ethanolic hydrochloric acid, gives keto lactone 6a, uncontaminated with lactonic alcohol 7a.Annelation of 6a with (2-methoxyphenoxy)methyl vin

Full text of DOI:10.1021/jo00223a001

Products guided by the article

Product name:7-(2-Methoxy-phenoxy)-3a,4,5,6,9,10-hexahydro-3H-furo[3,4-j]isoquinoline-1,8-dione

Cas No:98689-11-3

R&D Labs maybe for 98689-11-3

guide(suzhou) fine materials co. ltd

Contact:0512-80972173

Address:21st Building, No.369 Lushan Rd, New District Suzhou China 215129
shijiazhuang baisheng chem co.; ltd

Contact:86-0311-80790826

Address:shijiazhuang hebei
TIANJIN DONGRUXIANG MINERALS MARKETING CO.,LTD(expird)

Contact:22-58516360

Address:tianjin
Henan Techway Chemical Co.,Ltd.

website:http://www.techwaychem.com

Contact:+86-371-66380080

Address:No.27 Shunhe Road,
Shandong Dayi Chemical Co., Ltd.

website:http://www.dayi.com.cn

Contact:+86- 535-7388728. 15306386031

Address:No 1 Danya west road, Laiyang City, Shandong province

Relevant to this article

Synthesis of spirocyclic thiazolidinediones using ring-closing metathesis and one-pot sequential ring-closing/cross metathesis

Doi:10.1039/c0ob01248c
(2011)
Quinolizidinyl derivatives of bi- and tricyclic systems as potent inhibitors of acetyl- and butyrylcholinesterase with potential in Alzheimer's disease

Doi:10.1016/j.ejmech.2011.02.071
(2011)
A green expedient synthesis of pyridopyrimidine-2-thiones and their antitubercular activity

Doi:10.1016/j.bmcl.2011.03.045
(2011)
CHIRAL AMINAL TEMPLATES 3. DIASTEREOSELECTIVITY OF ORGANOMETALLIC ATTACK ON ALDEHYDES BEARING A CHIRAL IMIDAZOLIDINE GROUP

Doi:10.1016/S0957-4166(00)86314-4
(1990)
Fluorocarbocyclic nucleosides: Synthesis and antiviral activity of 2'- and 6'-fluorocarbocyclic 2'-deoxy guanosines

Doi:10.1021/jm00107a006
(1991)
Inclusion compounds of p - Tert -butylcalixarenes: Structures, kinetics, and selectivity

Doi:10.1021/cg2004084
(2011)

Article Doi