
Journal of Organic Chemistry p. 5159 - 5166 (1985)
Update date:2022-08-05
Topics:
Hecker, Scott J.
Heathcock, Clayton H.
An approach to the hypocholesterolemic agent mevinolin (1b) is presented which utilizes an intramolecular Diels-Alder strategy for construction of the hexahydronaphthalene moiety.Alkylation of diene alcohol 11 with 1-chloro-3-phosphoranylidene-2-propanone
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Doi:10.1016/S0040-4020(01)96563-9
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(1959)