Journal of Organic Chemistry p. 130 - 135 (1986)
Update date:2022-08-04
Topics:
Hoffman, Robert V.
Jankowski, Bryan C.
Carr, C. Sean
Duesler, Eileen N.
α-(p-Nitrophenyl)sulfonoxy ketones can be converted to α-hydroxy ketals and α-hydroxy ketones by reaction with potassium carbonate and basic or acidic workup, respectively.They also react with amines to give α-amino ketones in high yields.Nonnucleophilic amines give an intramolecular aromatic substitution in the derived enolate.Factors which dictate the reaction patterns in these compounds are discussed.
View MoreOnlychem (Jinan)Biotech Co.,Ltd
Contact:86-531-83175885
Address:No. 44, Honglou South Road, Jinan,China
Contact:(1) 206-3550089
Address:5115 NE 8TH PL, Renton, WA 98059 USA
Beijing Mesochem Technology Co.,LTD
website:http://www.mesochem.com
Contact:0086-10-57862036
Address:2301, Floor 23, Building 9 Lippo Plaza, Yard 8 Ronghua Middle Road, ETDZ, Beijing, China
Tianjin Pharmacn Medical Technology Co.,Ltd.
Contact:86-22-60122566ext.866(English),23359620
Address:Green Industrial Base, 6 Haitaifazhan Sixth Rd., Huayuan Industrial Area, Tianjin, 300384, China
Contact:0571-
Address:zhejing
Doi:10.1021/jo01144a011
(1951)Doi:10.1055/s-0036-1588557
(2017)Doi:10.1002/jps.2600501009
(1961)Doi:10.1515/znb-2016-0271
(2017)Doi:10.1021/jm00153a020
(1986)Doi:10.1023/A:1010194119452
(1999)