Syntheses and Properties of Oligo-L-leucines Containing α-Aminoisobutyric Acid Residues. The Novel Strategy for Solubility Improvement in Helical Oligopeptides Based on the Restriction of the Values of the Backbone Dihedral Angles Φ and Ψ of α-Aminoisobut

Article abstract of DOI:10.1246/bcsj.58.1473

In order to provide a succinct demonstration of the usefulness of a new strategy for solubility improvement in protected peptide fragments included in α-helical regions of proteins, model oligo(Leu)s containing Aib or Ala residues were prepared by stepwis