An unexpected and green synthetic protocol for ethyl 1-aroyl/aroylmethyl-5- methyl-3-methylthiopyrazole-4-carboxylates: High regioselectivity in alkylation and acylation reactions between n-1 and n-2 of a pyrazole ring

Article abstract of DOI:10.1002/jccs.200500143

Two series, totaling twelve, of new compounds, ethyl 1-aroyl/(aroylmethyl)- 5-methyl-3-methylthiopyrazole-4-carboxylates (5/6), have been synthesized via highly regioselectively acylation and alkylation reactions of ethyl 3-methyl-5-methylthio-1H-pyrazole