The Reaction of Acetophenones with Manganese(III) Acetate

Article abstract of DOI:10.1246/bcsj.54.1757

The reaction of 4'-methoxyacetophenone with manganese(III) acetate in the presence of ammonium chloride yielded 2-chloro-4'-methoxyacetophenone (2a) and 2,2-dichloro-4'-methoxyacetophenone (3a).The reaction of 2a with these reagents gave 3a, 4'-methoxy-2,2,2-trichloroacetophenone and 1,4-bis(4-methoxyphenyl)2,2,3,3,-tetrachloro-1,4-butanedione (8a).The reactions of 2a and 2-bromoacetophenone with manganese(III) acetate yielded the corresponding 2,3-dihalo-1,4-diphenyl-1,4-butanediones, 1,4-diphenyl-2-halo-2-butene-1,4-diones, 2,3-dihalo-2-butene-1,4-diones, 2,2-dibromoacetophenone, and 8a.The reaction pathways are discussed.