Palladium Cross-Coupling Reactions of Aryl Fluorosulfonates: An Alternative to Triflate Chemistry

Article abstract of DOI:10.1021/jo00011a010

A new and efficient electrophilic partner for palladium(0)-catalyzed cross coupling is reported.Aryl fluorosulfonates are readily prepared in high yield by treatment of the appropriate phenol with fluorosulfonate anhydride.The palladium-catalyzed coupling reactions of these fluorosulfonates with vinyl- and aryltin reagents, as well as organozinc chlorides, takes place under mild conditions in a regio- and stereoselective manner.