Oxidative decarboxylation of α-amino and α-hydroxy acids using copper(II) bromide-lithium tert-butoxide

Article abstract of DOI:10.1055/s-1996-4267

α-Monoalkyl α-amino acids were oxidized to the corresponding alkanenitriles in good yields by treatment with copper(II) bromide-lithium tert-butoxide. The oxidation of α,α-disubstituted α-amino and α-hydroxy acids also gave the corresponding ketones.