Chiral Environment around the Metal Center Observed by the Epoxidation with the Iron Complexes of Bleomycin and the Synthetic Analogue

Article abstract of DOI:10.1246/cl.1989.611

cis-β-Methylstyrene is oxidized either with the Fe(III)-H2O2 or with the Fe(II)-O2 complex systems of bleomycin and the synthetic model ligand PYML-6 to give optically active epoxide, showing that the environment around the iron-nucleus is chiral enough to cause asymmetric epoxidation.