Tetrahedron p. 17241 - 17246 (1997)
Update date:2022-08-17
Topics:
Maturano, Marie Dolores
Bongibault, Véronique
Willson, Michèle
Klaébé, Alain
Fournier, Didier
The NMR study of the reaction of methylparathion with thiol (glutathione) and a tertiary amine shows unambiguously a sequential transfer of the methyl group firstly to the amine and secondly to the thiol. The reaction stops after a single demethylation. This observation may account for regiospecificity of some glutathione S-transferases.
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