Heterocycles p. 277 - 280 (1994)
Update date:2022-08-29
Topics:
Hirai, Koichi
Iwano, Yuji
Mikoshiba, Isamu
Koyama, Hiroo
Nishi, Takahide
A 1β-methylcarboxylate (1) which is a requisite intermediate for the synthesis of the 1β-methylcarbapenem was obtained in an efficient manner by the coupling reaction of a Z(O)-pyridylthiosilyl enol ether and a 4-acetoxyazetidinone derivative in the presence of ZnCl2 in CH2Cl2.The reactive silyl enol ether was prepared by the reverse addition method in high yield.
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Doi:10.1002/jhet.5570390625
(2002)Doi:10.1515/hc-2015-0107
(2015)Doi:10.1016/j.chemosphere.2004.07.028
(2004)Doi:10.1016/S0040-4020(97)00102-6
(1997)Doi:10.1021/j100182a037
(1992)Doi:10.1002/chem.202002599
(2021)
