Asymmetric Baeyer-Villiger reaction: Diastereodifferentiating peracid oxidation of chiral acetal in the presence of Lewis acid

Article abstract of DOI:10.1016/S0040-4039(97)01338-5

Oxidation of 2 with m-chloroperbenzoic acid in the presence of SnCl₄ at -78°C followed by hydrolysis afforded optically active 4 in a quantitative yield. The enantiomeric excess tee) of 4 largely depended on the reaction solvent, the chiral dio