Journal of the Chemical Society. Chemical communications p. 1534 - 1535 (1987)
Update date:2022-08-11
Topics:
Barluenga, Jose
Fernandez, Jose R.
Yus, Miguel
The lithiation of 3-chloropropanal diethyl acetal (easily prepared from acrolein) at -78 deg C with lithium naphthalenide followed by reaction with various carbonyl compounds, and final oxidation with m-chloroperbenzoic acid leads to γ-susbstituted butyrolactones.
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