The application of 1H nuclear magnetic resonance spectroscopy for the determination of the absolute configuration of chiral carboxylic acids

Article abstract of DOI:10.1016/0040-4020(96)00516-9

A modification of a model, described by Mosher allows a correlation to be made between the absolute configuration of a range of simple chiral carboxylic acids with the corresponding nmr chemical shifts of their esters derived from (S)-methyl mandelate.