A short diastereoselective synthesis of the natural (2R, 3R, 4R)-2-hydroxymethyl-3,4-dihydroxypyrrolidine

DOI: 10.1016/S0040-4039(00)76651-2

Source and publish data:

Tetrahedron Letters p. 2889 - 2890 (1994)

Update date:2022-08-24

Topics:

Authors:

Griffart-Brunet, Dominique

Langlois, Nicole

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Article abstract of DOI:10.1016/S0040-4039(00)76651-2

1,4-Dideoxy-1,4-imino-D-arabinitol 1, a glycosidase inhibitor constituent of Arachniodes standishii 1 and angylocalyx boutiqueanus2 was synthesized from (S)-pyroglutamic acid through regioselective ring opening of the epoxide 3.

Full text of DOI:10.1016/S0040-4039(00)76651-2

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