Cesium hydroxide catalyzed addition of alcohols and amine derivatives to alkynes and styrene

Article abstract of DOI:10.1016/S0040-4039(99)01133-8

In the presence of catalytic amounts of cesium hydroxide (CsOH · H₂O), alcohols, substituted anilines and heterocyclic amines undergo an addition in NMP to phenylacetylene leading to functionalized enol ethers and enamines. Anilines add to styrene (90-120°C, 12-14 h) leading to N-substituted anilines in satisfactory yields.