1
70
ZAHED KARIMI-JABERI et al.
Conclusion
In conclusion this paper describes a convenient and efficient process for the synthesis of
2
-substitued benzimidazoles by one-pot reaction of o-phenylenediamine with aldehydes in
the presence of boric acid in water. This method offers some advantages in terms of
simplicity of performance, using water as solvent, low reaction times, low cost and it
follows along the line of green chemistry. The catalyst is readily available and inexpensive
and can conveniently be handled and removed from the reaction mixture. We believe that
this procedure is convenient, economic and a user-friendly process for the synthesis of
substituted imidazoles of biological and medicinal importance.
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Karimi-Jaberi, Zahed
