Preparation of polyfunctional ketones by a cobalt(II) mediated carbonylation of organozinc reagents

DOI: 10.1016/0040-4039(95)01802-O

Source and publish data:

Tetrahedron Letters p. 8411 - 8414 (1995)

Update date:2022-08-28

Topics:

Authors:

Devasagayaraj

Knochel Knochel

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Article abstract of DOI:10.1016/0040-4039(95)01802-O

Functionalized organozinc halides can be efficiently carbonylated under atmospheric pressure in the presence of cobalt(II) bromide in THF:NMP leading to polyfunctional symmetrical ketones in 56-80% yield.

Full text of DOI:10.1016/0040-4039(95)01802-O

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