Preparation of polyfunctional ketones by a cobalt(II) mediated carbonylation of organozinc reagents

Article abstract of DOI:10.1016/0040-4039(95)01802-O

Functionalized organozinc halides can be efficiently carbonylated under atmospheric pressure in the presence of cobalt(II) bromide in THF:NMP leading to polyfunctional symmetrical ketones in 56-80% yield.