FACILE CONVERSION OF 1,3-DISUBSTITUTED THIOUREAS TO THE CORRESPONDING UREAS BY SUPEROXIDE RADICAL ANION (O2.-) IN DIMETHYL SULFOXIDE

Article abstract of DOI:10.1246/cl.1984.309

Treatment of 1,3-disubstituted thioureas with superoxide radical anion (O2^.-) at 20 deg C in dimethyl sulfoxide resulted in the formation of 1,3-disubstituted ureas in excellent yields.The desulfurization appears to proceed by the formation of peroxy-sulfur intermediates such as peroxy-sulfenate, -sulfinate and/or -sulfonate.