PLATINUM COMPLEX CATALYZED SYNTHESIS OF UREA DERIVATIVES FROM NITROARENES AND AMINES UNDER CARBON MONOXIDE

Article abstract of DOI:10.1016/0022-328X(85)87437-4

N,N'-Diarylureas were obtained in good yields from nitroarenes and aminoarenes at 140 deg C under carbon monoxide (initial 60 kg cm^-2) in the presence of a catalytic amount of dichlorobis(triphenylphosphine)platinum(II), the yields of N,N'-diphenylurea, N,N'-bis(4-methylphenyl)urea, and N,N'-bis(4-chlorophenyl)urea were 65, 67 and 61percent, respectively.Benzimidazole derivatives were obtained by the intramolecular cyclization reaction.An attempted synthesis of unsymmetric ureas resulted in the formation of a mixture of symmetric and unsymmetric products.