Synthesis of functionalized γ-and δ-lactones via polymer-bound epoxides

Article abstract of DOI:10.1016/S0040-4039(97)01098-8

Solid phase synthesis of epoxides from alkenoic acids followed by ring-opening reactions with sodium azide or thiophenols and subsequent cleavage from the polymeric support afford γ- and δ-lactones in good yields and high purity.