The behaviour of qinghaosu (artemisinin) in the presence of non-heme iron(II) and (III)

Article abstract of DOI:10.1016/0040-4039(95)02142-6

In aprotic solvents with FeCl₃, FeCl₃/N-acetyl cysteine or FeCl₂, qinghaosu (artemisinin) undergoes rearrangement to give the tetrahydrofuran acetate, 4-hydroxydesoxoqinghaosu or the enol lactone as the major product on th