CROTYLZIRCONIUM DERIVATIVES AS A NEW REAGENT FOR THE THREO SELECTIVE SYNTHESIS OF β-METHYLHOMOALLYL ALCOHOLS

Article abstract of DOI:10.1016/S0040-4039(01)81780-9

Crotylzirconium derivatives, prepared from the reaction of crotylmagnesium chloride or crotyllithium with bis(cyclopentadienyl)zirconium dichloride, undergo a rapid reaction with aldehydes to afford the threo product predominantly.The ratio of Cram/anti-Cram product via this reagent is ca. 75/25 ca. 60/40.