Synthesis of aldehydes from carboxylic acids via N-methoxyimidoyl bromides: Deoximation of O-methyloximes

Article abstract of DOI:10.1055/s-1993-25903

Aldehydes are synthesized by hydrogenation and subsequent deoximation of substituted N-methoxyalkanimidoyl bromides, which are prepared in one pot by reaction of the corresponding carboxylic acids with methoxyamine and triphenylphosphine carbon tetrabromide. Regeneration of aldehydes and ketones from O-methyloximes under mild conditions is also described.